AKT1S1 Polyclonal Antibody (20 μl)

Cat. #: 1477S
Availability: In Stock
$119.00
-+
Product Category:   Knockdown Validated Polyclonal Antibody
Synonyms:   AKT1 Substrate 1; 40 kDa Proline-Rich AKT Substrate; Proline-Rich AKT1 Substrate 1; PRAS40; Proline-Rich Akt Substrate, 40 kDa; AKT1 Substrate 1 (Proline Rich); AKT1 Substrate 1 (Proline-Rich); Lobe
UniProt Entry:   Q96B36
NCBI Gene Entry:   84335
Molecular Weight:   40 kDa
Clonality:   Rabbit polyclonal antibody
Species Reactivity:   Human
Applications:   WB
Recommended Dilution:   WB 1:1000
Immunogen:   Recombinant fragment of human AKT1S1
Isotype:   Rabbit IgG 
Storage Buffer:   Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:   At –20°C
Background:   AKT1S1 is a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can induce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
Documents: Please contact us to request the manual

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