ATG7 Polyclonal Antibody (20 μl)

ATG7 Polyclonal Antibody (20 μl)

Cat. #: 1737S
Availability: In Stock
$119.00
-+
Product Category:    Knockdown Validated Polyclonal Antibody
Synonyms:    Autophagy Related 7; Ubiquitin-Activating Enzyme E1-Like Protein; Ubiquitin-Like Modifier-Activating Enzyme ATG7; ATG12-Activating Enzyme E1 ATG7; APG7L; HAGP7; ATG7 Autophagy Related 7 Homolog (S. Cerevisiae); APG7 Autophagy 7-Like (S. Cerevisiae); Autophagy-Related Protein 7; APG7 Autophagy 7-Like; APG7-LIKE; APG7-Like; GSA7
UniProt Entry:    O95352
NCBI Gene Entry:    10533
Molecular Weight:    78 kDa
Clonality:    Rabbit polyclonal antibody
Species Reactivity:    Human
Applications:    WB
Recommended Dilution:    WB 1:1000
Immunogen:    Recombinant fragment of human ATG7
Isotype:    Rabbit IgG 
Storage Buffer:    Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:    At –20°C
Background:    ATG7 gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Documents:    Request a manual/MSDS

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