HDAC4 Polyclonal Antibody (20 μl)

HDAC4 Polyclonal Antibody (20 μl)

Cat. #: 3214S
Availability: In Stock
$119.00
-+
Product Category:    Knockdown Validated Polyclonal Antibody
Synonyms:    Histone Deacetylase 4; EC 3.5.1.98; HD4; Brachydactyly-Mental Retardation Syndrome; Histone Deacetylase A; KIAA0288;HA6116; HDAC-4; HDAC-A; HDACA; AHO3; BDMR
UniProt Entry:    P56524
NCBI Gene Entry:    9759
Molecular Weight:    140 kDa
Clonality:    Rabbit polyclonal antibody
Species Reactivity:    Human
Applications:    WB
Recommended Dilution:    WB 1:1000
Immunogen:    Recombinant fragment of human HDAC4
Isotype:    Rabbit IgG 
Storage Buffer:    Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:    At –20°C
Background:    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Documents:    Request a manual/MSDS

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