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Product Category: | Knockdown Validated Polyclonal Antibody |
Synonyms: | Histone Deacetylase 7; Histone Deacetylase 7A; EC 3.5.1.98;HDAC7A; HD7; HD7A; HD7a |
UniProt Entry: | Q8WUI4 |
NCBI Gene Entry: | 51564 |
Molecular Weight: | 124 kDa |
Clonality: | Rabbit polyclonal antibody |
Species Reactivity: | Human |
Applications: | IC |
Recommended Dilution: | IC 1:50 |
Immunogen: | Recombinant fragment of human HDAC7 |
Isotype: | Rabbit IgG |
Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
Storage: | At –20°C |
Background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC7 protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Documents: | Request a manual/MSDS |