HDAC7 Polyclonal Antibody (20 μl)

HDAC7 Polyclonal Antibody (20 μl)

Cat. #: 3217S
Availability: In Stock
$119.00
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Product Category:    Knockdown Validated Polyclonal Antibody
Synonyms:    Histone Deacetylase 7; Histone Deacetylase 7A; EC 3.5.1.98;HDAC7A; HD7; HD7A; HD7a
UniProt Entry:    Q8WUI4
NCBI Gene Entry:    51564
Molecular Weight:    124 kDa
Clonality:    Rabbit polyclonal antibody
Species Reactivity:    Human
Applications:    IC
Recommended Dilution:    IC 1:50
Immunogen:    Recombinant fragment of human HDAC7
Isotype:    Rabbit IgG 
Storage Buffer:    Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:    At –20°C
Background:    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC7 protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents:    Request a manual/MSDS

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