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Product Category: | Knockdown Validated Polyclonal Antibody |
Synonyms: | Catalase; EC 1.11.1.6; Epididymis Secretory Sperm Binding Protein |
UniProt Entry: | P04040 |
NCBI Gene Entry: | 847 |
Molecular Weight: | 60 kDa |
Clonality: | Rabbit polyclonal antibody |
Species Reactivity: | Human |
Applications: | WB/IC |
Recommended Dilution: | WB 1:1000/ IC 1:200 |
Immunogen: | Recombinant fragment of human CAT |
Isotype: | Rabbit IgG |
Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
Storage: | At –20°C |
Background: | CAT gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. |
Documents: | Request a manual/MSDS |