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Product Category: | Knockdown Validated Polyclonal Antibody |
Synonyms: | Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1;Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog) ; Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian) ; Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog;Epidermal Growth Factor Receptor Tyrosine Kinase Domain;Cell Proliferation-Inducing Protein 61; Cell Growth Inhibiting Protein 40; EC 2.7.10; NISBD2; PIG61; MENA |
UniProt Entry: | P00533 |
NCBI Gene Entry: | 1956 |
Molecular Weight: | 175 kDa |
Clonality: | Rabbit polyclonal antibody |
Species Reactivity: | Human |
Applications: | IC |
Recommended Dilution: | IC 1:50 |
Immunogen: | Recombinant fragment of human EGFR |
Isotype: | Rabbit IgG |
Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
Storage: | At –20°C |
Background: | EGFR protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. |
Documents: | Please contact us to request the manual |