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Product Category: | Knockdown Validated Polyclonal Antibody |
Synonyms: | GATA Binding Protein 3; Trans-Acting T-Cell-Specific Transcription Factor GATA-3; GATA-Binding Factor 3; GATA-Binding Protein 3; HDRS; HDR |
UniProt Entry: | P23771 |
NCBI Gene Entry: | 2625 |
Molecular Weight: | 48 kDa |
Clonality: | Rabbit polyclonal antibody |
Species Reactivity: | Human |
Applications: | IC |
Recommended Dilution: | IC 1:200 |
Immunogen: | Recombinant fragment of human GATA3 |
Isotype: | Rabbit IgG |
Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
Storage: | At –20°C |
Background: | GATA3 is a transcriptional factor that binds to the enhancer elements of all 4 T-cell antigen receptor genes. GATA3 is highly expressed in naive,freshly activated cells and Th2 lineage cells and thought to be necessary and sufficient for Th2 cytokine gene expression. GATA3 and TBET interfer with each other to regulate gene expression. |
Documents: | Please contact us to request the manual |