ITGA4 Polyclonal Antibody (20 μl)  

ITGA4 Polyclonal Antibody (20 μl)  

Cat. #: 3734S
Availability: In Stock
$119.00
-+
Product Category:    Knockdown Validated Polyclonal Antibody
Synonyms:    Integrin Subunit Alpha 4; Alpha 4 Subunit Of VLA-4 Receptor;CD49 Antigen-Like Family Member D; VLA-4 Subunit Alpha;Integrin Alpha-IV; Integrin Alpha-4; CD49D; Integrin, Alpha 4 (Antigen CD49D, Alpha 4 Subunit Of VLA-4 Receptor); Very Late Activation Protein 4 Receptor, Alpha 4 Subunit; Antigen CD49D, Alpha-4 Subunit Of VLA-4 Receptor; 269C Wild Type;CD49d Antigen; Antigen CD49D; IA4
UniProt Entry:    P13612 
NCBI Gene Entry:    3676 
Molecular Weight:    70, 140, 150kDa 
Clonality:    Rabbit polyclonal antibody
Species Reactivity:    Human
Applications:    IC
Recommended Dilution:    IC 1:100
Immunogen:    Recombinant fragment of human ITGA4 
Isotype:    Rabbit IgG 
Storage Buffer:    Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:    At –20°C
Background:    ITGA4 gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
Documents:    Request a manual/MSDS

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