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Product Category: | Knockdown Validated Polyclonal Antibody |
Synonyms: | Janus Kinase 2; Tyrosine-Protein Kinase JAK2; EC 2.7.10.2; JAK-2; Janus Kinase 2 (A Protein Tyrosine Kinase); EC 2.7.10;THCYT3; JTK10 |
UniProt Entry: | O60674 |
NCBI Gene Entry: | 3717 |
Molecular Weight: | 125 kDa |
Clonality: | Rabbit polyclonal antibody |
Species Reactivity: | Human |
Applications: | IC/F |
Recommended Dilution: | IC 1:100 / F 1:50 |
Immunogen: | Recombinant fragment of human JAK2 |
Isotype: | Rabbit IgG |
Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
Storage: | At –20°C |
Background: | JAK2 gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. |
Documents: | Please contact us to request the manual |