NFKBIA Monoclonal Antibody (20 μl) 

NFKBIA Monoclonal Antibody (20 μl) 

Cat. #: 5231S
Availability: In Stock
$119.00
-+
Product Category:   Knockdown Validated Monoclonal Antibody
Synonyms:   NFKB Inhibitor Alpha; NF-Kappa-B Inhibitor Alpha; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Alpha; Major Histocompatibility Complex Enhancer-Binding Protein MAD3; I-Kappa-B-Alpha; IkappaBalpha; IkB-Alpha; NFKBI; IKBA; Nuclear Factor Of Kappa Light Chain Gene Enhancer In B-Cells; EDAID2; MAD-3; MAD3
UniProt Entry:   P25963 
NCBI Gene Entry:   4792 
Molecular Weight:   39 kDa
Clonality:   Mouse Monoclonal antibody
Species Reactivity:   Human
Applications:   WB/IC
Recommended Dilution:   Western blotting (WB): 1:1,000
Immunocytochemistry (IC): 1:100
Immunogen:   Recombinant fragment of human NFKBIA 
Isotype:   Mouse IgG
Storage Buffer:   Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:   At –20°C
Background:   NFKBIA gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Documents: Please contact us to request the manual

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