PARP1 Polyclonal Antibody (20 μl)  

Cat. #: 6161S
Availability: In Stock
$119.00
-+
Product Category:   Knockdown Validated Polyclonal Antibody
Synonyms:   Poly(ADP-Ribose) Polymerase 1; ADP-Ribosyltransferase (NAD+; Poly (ADP-Ribose) Polymerase) ; ADP-Ribosyltransferase Diphtheria Toxin-Like 1; Poly (ADP-Ribose) Polymerase Family, Member 1; Protein Poly-ADP-Ribosyltransferase PARP1; DNA ADP-Ribosyltransferase PARP1;NAD(+) ADP-Ribosyltransferase 1; Poly [ADP-Ribose] Polymerase 1; Poly[ADP-Ribose] Synthase 1; EC 2.4.2.30;ADPRT 1; PARP-1; ADPRT; ARTD1 ; PPOL; ADP-Ribosyltransferase NAD(+); Poly(ADP-Ribosyl)Transferase;Poly(ADP-Ribose) Synthetase; EC 2.4.2.- ; PADPRT-1; EC 2.4.2;ADPRT1; PARP
UniProt Entry:   P09874 
NCBI Gene Entry:   142 
Molecular Weight:   89, 116 kDa 
Clonality:   Rabbit polyclonal antibody
Species Reactivity:   Human
Applications:   WB/IC/F 
Recommended Dilution:   WB 1:1000 / IC 1:400 / F 1:200
Immunogen:   Recombinant fragment of human PARP1
Isotype:   Rabbit IgG 
Storage Buffer:   Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:   At –20°C
Background:   PARP1 gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Documents: Please contact us to request the manual

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