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Product Category: | Knockdown Validated Polyclonal Antibody |
Synonyms: | Ribosomal Protein S6 Kinase A3; MAP Kinase-Activated Protein Kinase 1b; Insulin-Stimulated Protein Kinase 1; Ribosomal Protein S6 Kinase Alpha-3; MAPK-Activated Protein Kinase 1b;Ribosomal S6 Kinase 2; MAPKAP Kinase 1b; S6K-Alpha-3; EC 2.7.11.1; MAPKAPK-1b; MAPKAPK1B; P90-RSK 3; Pp90RSK2;ISPK-1; RSK-2; RSK2; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 3; Epididymis Secretory Sperm Binding Protein; 90 KDa Ribosomal Protein S6 Kinase 3; S6K-Alpha3; EC 2.7.11; P90-RSK2; P90RSK3; MRX19; ISPK1; HU-3; RSK; CLS |
UniProt Entry: | P51812 |
NCBI Gene Entry: | 6197 |
Molecular Weight: | 90 kDa |
Clonality: | Rabbit polyclonal antibody |
Species Reactivity: | Human |
Applications: | WB/IC/F |
Recommended Dilution: | WB 1:1000 / IC 1:100 / F 1:50 |
Immunogen: | Recombinant fragment of human RPS6KA3 |
Isotype: | Rabbit IgG |
Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
Storage: | At –20°C |
Background: | RPS6KA3 gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). |
Documents: | Please contact us to request the manual |