TSC2 Polyclonal Antibody (20 μl)  

Cat. #: 7712S
Availability: In Stock
$119.00
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Product Category:   Knockdown Validated Polyclonal Antibody
Synonyms:   TSC Complex Subunit 2; Protein Phosphatase 1, Regulatory Subunit 160; Tuberous Sclerosis 2 Protein; Tuberin; TSC4;Tuberous Sclerosis 2; PPP1R160; LAM
UniProt Entry:    P49815
NCBI Gene Entry:   7249
Molecular Weight:   200 kDa
Clonality:   Rabbit polyclonal antibody
Species Reactivity:   Human
Applications:   WB/IC/F 
Recommended Dilution:   WB 1:1000 / IC 1:200 / F 1:500
Immunogen:   Recombinant fragment of human TSC2
Isotype:   Rabbit IgG 
Storage Buffer:   Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:   At –20°C
Background:   Mutations in TSC2 gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Documents: Please contact us to request the manual

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