Adenovirus PIM1 (200 µl)

Adenovirus PIM1 (200 µl)

Cat. #: M1066
Availability: In Stock
$685.00
-+
Product Category:  
Human Adenovirus Type5 (dE1/E3) expressing Pim-1 Oncogene (PIM1) under a CMV promoter.
Description: Pim-1 Oncogene (PIM1), pre-packaged adenovirus, ready to ship and ready to use format.
Gene: Pim-1 Oncogene
NCBI Acc. #: NM_002648
Gene ID: 5292
GI Number: 4505810
Fusion Tag: C-terminus V5 epitope tag
Promoter: CMV
Titer: 1E+10~1E+11 PFU/ml
Storage Buffer: DMEM with 2.5% BSA, 2.5% glycerol
Background:   The protein encoded by PIM1 gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).
Documents:   Request a manual/MSDS

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