CASP7 Polyclonal Antibody (20 μl)

CASP7 Polyclonal Antibody (20 μl)

Cat. #: 1177S
Availability: In Stock
Product Category:   Knockdown Validated Polyclonal Antibody
Synonyms:   Caspase 7; Caspase 7, Apoptosis-Related Cysteine Peptidase; Caspase 7, Apoptosis-Related Cysteine Protease; ICE-Like Apoptotic Protease 3; Caspase-7; ICE-LAP3; CASP-7; CMH-1; MCH3; Apoptotic Protease MCH-3; Apoptotic Protease Mch-3; EC; EC 3.4.22; LICE2
UniProt Entry:   P55210 
NCBI Gene Entry:   840 
Molecular Weight:   20, 35 kDa 
Clonality:   Rabbit polyclonal antibody
Species Reactivity:   Human
Applications:   WB
Recommended Dilution:   WB 1:1000
Immunogen:   Recombinant fragment of human CASP7
Isotype:   Rabbit IgG 
Storage Buffer:   Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide  
Storage:   At –20°C
Background:   CASP7 gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Documents:   Request a manual/MSDS

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