Human EGFR (Epidermal Growth Factor Receptor) ELISA Kit (96T)

Human EGFR (Epidermal Growth Factor Receptor) ELISA Kit (96T)

Cat. #: E-EL-H0060
Availability: 3-5 Business Days
$495.00
-+
Product Name:Human EGFR ELISA Kit    
Synonyms:  
EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Background:
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
Species:
Human
Detection Range:
0.313~20ng/mL
Sensitivity:
0.188ng/mL
Documents:
Request a manual/MSDS

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