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| Product Category: | Knockdown Validated Polyclonal Antibody |
| Synonyms: | Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit;Histone-Lysine N-Methyltransferase EZH2; Lysine N-Methyltransferase 6 ; Enhancer Of Zeste Homolog 2; EC 2.1.1.43; ENX-1; KMT6; Enhancer Of Zeste (Drosophila) Homolog 2; Enhancer Of Zeste Homolog 2 (Drosophila) ; EC 2.1.1.43') ; EC 2.1.1; EZH2b; KMT6A; ENX1; WVS2; WVS |
| UniProt Entry: | Q15910 |
| NCBI Gene Entry: | 2146 |
| Molecular Weight: | 98 kDa |
| Clonality: | Rabbit polyclonal antibody |
| Species Reactivity: | Human |
| Applications: | WB/IC |
| Recommended Dilution: | WB 1:1000/ IC 1:100 |
| Immunogen: | Recombinant fragment of human EZH2 |
| Isotype: | Rabbit IgG |
| Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
| Storage: | At –20°C |
| Background: | EZH2 gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. |
| Documents: | Request a manual/MSDS |
