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| Product Category: | Human lentivirus expressing GPBAR1 |
| Description: | Premade lentivirus for over-expression of human GPBAR1 and control, ready to use format. |
| Gene Name: | G protein-coupled bile acid receptor 1 |
| Gene Symbol: | GPBAR1 |
| Synonyms: | BG37; TGR5; M-BAR; GPCR19; GPR131 |
| ACCN: | NM_170699.3 |
| Gene ID: | 151306 |
| Vector: | VP001-CMV-MCS-EF1-ZsGreen-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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