GABBR1 Rabbit pAb (20 μl)

GABBR1 Rabbit pAb (20 μl)

Brand: Abclonal
Cat. #: A10504
Availability: In Stock
$108.00
-+
Reactivity: Human, Mouse, Rat    
Applications: WB, IF/IC, ELISA    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Polyclonal antibody    
Gene Name: gamma-aminobutyric acid type B receptor subunit 1
Gene Symbol: GABBR1
Synonyms: GB1; GPRC3A; GABABR1; GABBR1-3; GABBR1
Gene ID: 2550
UniProt ID: Q9UBS5
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human GABBR1 (NP_068703.1).
Dilution: WB 1:1000-1:2000; IF/IC 1:100-1:500
Purification Method: Affinity purification
Concentration: 1.71 mg/ml
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-GABBR1 antibody




Background

This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.




Images

GABBR1 antibodyWestern blot analysis of various lysates using GABBR1 Rabbit pAb (A10504) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.
Immunofluorescence analysis of SH-SY5Y cells using GABBR1 Rabbit pAb (A10504) at dilution of 1:300 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.



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