ABflo® 488 Rabbit anti-Human CD112/Nectin-2 mAb (100 T)

Brand: Abclonal
Cat. #: A24327
Availability: In Stock

$218.00

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Description

Reactivity:	Human
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	nectin cell adhesion molecule 2
Gene Symbol:	NECTIN2
Synonyms:	HVEB; PRR2; CD112; PVRL2; PVRR2
Gene ID:	5819
UniProt ID:	Q92692
Clone ID:	9X4B6
Immunogen:	Recombinant Protein corresponding to a sequence within amino acids 32-158 of human CD112/Nectin-2 (NP_001036189.1).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.01 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-NECTIN2 Antibody

Background

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Images

	Flow cytometry:1×10^6 MOLT-4 cells (negative control,Left) and MCF-7 cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human CD112/Nectin-2 mAb(A24327,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry:1×10^6 MCF-7 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD112/Nectin-2 mAb(A24327,5 μl/Test,right).