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ABflo® 488 Rabbit anti-Human CD261/TRAIL-R1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | TNF receptor superfamily member 10a |
| Gene Symbol: | TNFRSF10A |
| Synonyms: | DR4; APO2; CD261; TRAILR1; TRAILR-1 |
| Gene ID: | 8797 |
| UniProt ID: | O00220 |
| Clone ID: | 6V9G2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 124-232 of human CD261/TRAIL-R1 (NP_003835.3). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TNFRSF10A Antibody |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Images
 | Flow cytometry: 1×10^6 BEWO cells (negative control,left) and HeLa cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD261/TRAIL-R1 mAb (A24700,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 HeLa cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD261/TRAIL-R1 mAb (A24700,5 μl/Test,right). |
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