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ABflo® 488 Rabbit anti-Human CD71 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | transferrin receptor |
| Gene Symbol: | TFRC |
| Synonyms: | T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46 |
| Gene ID: | 7037 |
| UniProt ID: | P02786 |
| Clone ID: | 3K10S3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-250 of human CD71 (NP_003225.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TFRC Antibody |
Background
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified.
Images
 | Flow cytometry: 1×10^6 SH-SY5Y cells (Low Expression,left) and K-562 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD71 mAb (A22301,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells was used as blank control (red line). |
 | Flow cytometry: 1×10^6 K-562 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD71 mAb (A22301,5 μl/Test,right). |
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