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ABflo® 488 Rabbit anti-Human ITGA1/CD49a mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | Integrin subunit alpha 1 |
| Gene Symbol: | ITGA1 |
| Synonyms: | VLA1; CD49a |
| Gene ID: | 3672 |
| UniProt ID: | P56199 |
| Clone ID: | 3M0Q0 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of human ITGA1/CD49a ( NP_852478.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ITGA1 Antibody |
Background
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
Images
 | Flow cytometry:1×10^6 K-562 cells (negative control,Left) and SH-SY5Y cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human ITGA1/CD49a mAb (A22691,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 SH-SY5Y cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human ITGA1/CD49a mAb (A22691,5 μl/Test,right). |
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