ABflo® 488 Rabbit anti-Human PTH1R mAb (100 T)

ABflo® 488 Rabbit anti-Human PTH1R mAb (100 T)

Brand: Abclonal
Cat. #: A26912
Availability: In Stock
$530.00
-+
Reactivity: Human    
Applications: FC    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Monoclonal Antibody    
Conjugation: ABflo® 488. Ex:491nm. Em:516nm.
Gene Name: parathyroid hormone 1 receptor
Gene Symbol: PTH1R
Synonyms: PFE; EKNS; PTHR; PTHR1
Gene ID: 5745
UniProt ID: Q03431
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-188 of human PTH1R (NP_000307.1).
Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Purification Method: Affinity purification
Concentration: 0.04 mg/ml
Buffer: PBS with 0.09% Sodium azide,0.2% BSA, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-PTH1R Antibody




Background

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.




Images

PTH1R  AntibodyFlow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Human PTH1R mAb (A26912,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry: 1×10^6 293T (Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human PTH1R mAb (A26912,5 μl/Test,right).



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