ABflo® 488 Rabbit anti-Mouse CD126/IL-6Rα chain mAb (100 T)

Brand: Abclonal
Cat. #: A25149
Availability: In Stock

$290.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	interleukin 6 receptor, alpha
Gene Symbol:	Il6ra
Synonyms:	Il6r; CD126; IL-6R; IL-6RA; IL-6R-alpha
Gene ID:	16194
UniProt ID:	P22272
Clone ID:	2B5H3
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 20-357 of mouse CD126/IL-6Rα chain (NP_034689.2).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.01 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-Il6ra antibody

Background

Enables interleukin-6 binding activity and interleukin-6 receptor activity. Involved in T-helper 17 cell lineage commitment and interleukin-6-mediated signaling pathway. Located in cell surface. Part of interleukin-6 receptor complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hyper IgE syndrome; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).

Images

	Flow cytometry: 1×10^6 C2C12 cells (Low Expression,left) and RAW 264.7 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD126/IL-6Rα chain mAb (A25149,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 RAW 264.7 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD126/IL-6Rα chain mAb (A25149,5 μl/Test,right).