ABflo® 488 Rabbit anti-Mouse CD262/TRAILR2 mAb (100 T)

Brand: Abclonal
Cat. #: A24374
Availability: In Stock

$140.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	tumor necrosis factor receptor superfamily, member 10b
Gene Symbol:	Tnfrsf10b
Synonyms:	MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B
Gene ID:	21933
UniProt ID:	Q9QZM4
Clone ID:	8W1V9
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 53-170 of mouse CD262/TRAILR2( NP_064671.2).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-Tnfrsf10b antibody

Background

Predicted to enable TRAIL receptor activity; identical protein binding activity; and protease binding activity. Predicted to be involved in TRAIL-activated apoptotic signaling pathway and positive regulation of apoptotic process. Predicted to act upstream of or within apoptotic process and regulation of apoptotic process. Predicted to be located in Golgi apparatus; cytosol; and membrane raft. Predicted to be active in cell surface and plasma membrane. Is expressed in bladder; liver; renal vasculature; urethra of female; and urethra of male. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervical cancer; hematologic cancer (multiple); and urinary bladder cancer. Orthologous to several human genes including TNFRSF10A (TNF receptor superfamily member 10a).

Images

	Flow cytometry:1×10^6 293F cells (negative control,left) and 293F(Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Mouse CD262/TRAILR2 mAb(A24374,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry:1×10^6 293F(Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD262/TRAILR2 mAb(A24374,5 μl/Test,right).