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ABflo® 488 Rabbit anti-Mouse CD56/NCAM mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | neural cell adhesion molecule 1 |
| Gene Symbol: | Ncam1 |
| Synonyms: | CD56; Ncam; E-NCAM; NCAM-1 |
| Gene ID: | 17967 |
| UniProt ID: | P13595 |
| Clone ID: | 1M8D4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-711 of mouse CD56 (NP_001106675.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Ncam1 antibody |
Background
Predicted to enable LRR domain binding activity and phosphatase binding activity. Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including homotypic cell-cell adhesion; positive regulation of calcium-mediated signaling; and regulation of exocyst assembly. Located in several cellular components, including external side of plasma membrane; growth cone; and neuronal cell body. Is expressed in several structures, including embryo mesenchyme; nervous system; sensory organ; skin; and urinary system. Human ortholog(s) of this gene implicated in bipolar disorder; middle cerebral artery infarction; and pancreatic cancer. Orthologous to human NCAM1 (neural cell adhesion molecule 1).
Images
 | Flow cytometry:1×10^6 L-929 cells(negative control,left) and Neuro-2a cells (right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD56/NCAM mAb(A23369,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained cells was used as blank control (red line). |
 | Flow cytometry:1×10^6 Neuro-2a cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD56/NCAM mAb(A23369,5 μl/Test,right). |
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