ABflo® 488 Rabbit anti-Mouse CD88/C5aR mAb (100 T)

Brand: Abclonal
Cat. #: A26710
Availability: In Stock

$218.00

Qty

Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	complement component 5a receptor 1
Gene Symbol:	C5ar1
Synonyms:	C5aR; C5r1; Cd88; D7Msu1
Gene ID:	12273
UniProt ID:	P30993
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-37 of mouse CD88/C5aR (NP_031603.2).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/ml
Buffer:	PBS with 0.09% Sodium azide,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-C5ar1 Antibody

Background

Enables complement component C5a receptor activity. Involved in several processes, including astrocyte activation; positive regulation of vascular endothelial growth factor production; and regulation of granulocyte chemotaxis. Acts upstream of or within defense response to Gram-positive bacterium; neutrophil chemotaxis; and response to peptidoglycan. Predicted to be located in several cellular components, including apical part of cell; basolateral plasma membrane; and cell surface. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; liver; neural ectoderm; and sensory organ. Orthologous to several human genes including OPRPN (opiorphin prepropeptide).

Images

	Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes (negative control,left) and C57BL/6 mouse bone marrow cells (right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD88/C5aR mAb (A26710,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 C57BL/6 mouse bone marrow cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD88/C5aR mAb (A26710,5 μl/Test,right).