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ABflo® 488 Rabbit anti-Mouse E-Cadherin/CD324 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | cadherin 1 |
| Gene Symbol: | Cdh1 |
| Synonyms: | Um; UVO; Ecad; ARC-1; E-cad; L-CAM |
| Gene ID: | 12550 |
| UniProt ID: | P09803 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 157-369 of mouse E-Cadherin/CD324 (NP_033994.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cdh1 antibody |
Background
This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8.
Images
 | Flow cytometry: 1×10^6 CHO-S cells (negative control,left) and CHO-S (Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Mouse E-Cadherin/CD324 mAb (A26483,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 CHO-S (Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse E-Cadherin/CD324 mAb (A26483,5 μl/Test,right). |
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