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ABflo® 488 Rabbit anti-Mouse FcγRI/CD64 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | Fc receptor, IgG, high affinity I |
| Gene Symbol: | Fcgr1 |
| Synonyms: | CD64; IGGHAFC; FcgammaRI |
| Gene ID: | 14129 |
| UniProt ID: | P26151 |
| Clone ID: | 9R9P3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-297 of mouse FcγRI/CD64 (NP_034316.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Fcgr1 antibody |
Background
Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; endocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver. Orthologous to several human genes including FCGR1A (Fc gamma receptor Ia).
Images
 | Flow cytometry: 1×10^6 BALB/C mouse splenocytes (negative control,left) and RAW 264.7 cells(right) were surface-stained with ABflo® 488 Rabbit anti-Mouse FcγRI/CD64 mAb(A23855,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 RAW 264.7 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse FcγRI/CD64 mAb(A23855,5 μl/Test,right). |
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