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ABflo® 488 Rabbit anti-Mouse Integrin alpha 1/CD49a mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | integrin alpha 1 |
| Gene Symbol: | Itga1 |
| Synonyms: | Vla1; CD49A; E130012M19Rik |
| Gene ID: | 109700 |
| UniProt ID: | Q3V3R4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of mouse Integrin alpha 1/CD49a (NP_001028400.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Itga1 antibody |
Background
CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.
Images
 | Flow cytometry: 1×10^6 NIH/3T3 cells (negative control,left) and Neuro-2a cells (right) were surface-stained with ABflo® 488 Rabbit anti-Mouse Integrin alpha 1/CD49a mAb (A26654,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 Neuro-2a cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse Integrin alpha 1/CD49a mAb (A26654,5 μl/Test,right). |
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