Reactivity: | Pig |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
Gene Name: | CD27 molecule |
Gene Symbol: | CD27 |
Synonyms: | N/A |
Gene ID: | 100520023 |
Clone ID: | 1K4H1 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of pig CD27. (NP_001265692.1). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-CD27 antibody |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Images
![]() | Flow cytometry:1×10^6 293F cells (negative control,Left) and 293F(Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Pig CD27 mAb(A23101,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells was used as blank control (red line). |
![]() | Flow cytometry:1×10^6 293F(Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Pig CD27 mAb(A23101,5 μl/Test,right). |
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