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ABflo® 594 Rabbit anti-Human CD200R mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
| Gene Name: | CD200 receptor 1 |
| Gene Symbol: | CD200R1 |
| Synonyms: | OX2R; MOX2R; CD200R; HCRTR2 |
| Gene ID: | 131450 |
| UniProt ID: | Q8TD46 |
| Clone ID: | 3B8P7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-240 of human CD200R (NP_740750.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD200R1 antibody |
Background
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.
Images
 | Flow cytometry: 1×10^6 Jurkat cells (negative control,left) and HEL cells (right) were surface-stained with ABflo® 594 Rabbit anti-Human CD200R mAb (A25712,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 HEL cells were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human CD200R mAb (A25712,5 μl/Test,right). |
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