| Reactivity: | Human |
| Applications: | IF/ICC, FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
| Gene Name: | CD84 molecule |
| Gene Symbol: | CD84 |
| Synonyms: | LY9B; hCD84; mCD84; SLAMF5 |
| Gene ID: | 8832 |
| UniProt ID: | Q9UIB8 |
| Clone ID: | 1Y2Y2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-225 of human CD84 (NP_001171808.1). |
| Dilution: | IF/ICC,1:50 - 1:200|FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD84 Antibody |
Background
This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Alternate splicing results in multiple transcript variants.
Images
![]() | Confocal imaging of HEL cells using ABflo® 594 Rabbit anti-Human CD84 mAb (A24580, dilution 1:200). DAPI was used for nuclear staining (Blue). Objective: 100x. |
![]() | Flow cytometry: 1×10^6 HAP1 cells (negative control,left) and Raji cells (right) were surface-stained with ABflo® 594 Rabbit anti-Human CD84 mAb (A24580,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 Raji cells were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human CD84 mAb (A24580,5 μl/Test,right). |
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