ABflo® 594 Rabbit anti-Mouse CD105/Endoglin mAb (100 T)

Brand: Abclonal
Cat. #: A25379
Availability: In Stock

$78.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 594. Ex:588nm. Em:604nm.
Gene Name:	endoglin
Gene Symbol:	Eng
Synonyms:	Endo; CD105; S-endoglin
Gene ID:	13805
UniProt ID:	Q63961
Clone ID:	4I8W5
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 27-581 of mouse CD105 (NP_031958.2).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-Eng antibody

Background

Enables protein homodimerization activity and transforming growth factor beta binding activity. Involved in several processes, including circulatory system development; positive regulation of cell differentiation; and regulation of gene expression. Acts upstream of or within circulatory system development and positive regulation of angiogenesis. Located in endothelial microparticle. Is expressed in several structures, including brain; cardiovascular system; extraembryonic vascular system; and lung. Used to study arteriovenous malformations of the brain and hereditary hemorrhagic telangiectasia. Human ortholog(s) of this gene implicated in arteriovenous malformation; arteriovenous malformations of the brain; breast cancer; hereditary hemorrhagic telangiectasia; and intracranial aneurysm. Orthologous to human ENG (endoglin).

Images

	Flow cytometry: 1×10^6 NIH/3T3 cells (negative control,left) and bEnd.3 cells (right) were surface-stained with ABflo® 594 Rabbit anti-Mouse CD105/Endoglin mAb (A25379,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 bEnd.3 cells were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Mouse CD105/Endoglin mAb (A25379,5 μl/Test,right).