| Reactivity: | Human, Monkey |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 610. Ex:421nm. Em:612nm. |
| Gene Name: | membrane spanning 4-domains A1 |
| Gene Symbol: | MS4A1 |
| Synonyms: | B1; S7; Bp35; CD20; FMC7; CVID5; LEU-16 |
| Gene ID: | 931 |
| UniProt ID: | P11836 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD20 mAb (NP_068769.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-MS4A1 Antibody |
Background
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Images
![]() | Flow cytometry: 1×10^6 Jurkat cells (negative control,left) and Daudi cells (right) were surface-stained with ABflo® 610 Rabbit anti-Human/Monkey CD20 mAb (A26466,5 μl/Test,orange line) or ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 Daudi cells were surface-stained with ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,left) or ABflo® 610 Rabbit anti-Human/Monkey CD20 mAb (A26466,5 μl/Test,right). |
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