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ABflo® 647 Rabbit anti-Human CD369/Dectin-1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | C-type lectin domain containing 7A |
| Gene Symbol: | CLEC7A |
| Synonyms: | BGR; CD369; CANDF4; SCARE2; DECTIN1; CLECSF12 |
| Gene ID: | 64581 |
| UniProt ID: | Q9BXN2 |
| Clone ID: | 9Z6T4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 66-247 of human CD369/Dectin-1 (NP_922938.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CLEC7A antibody |
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Images
 | Flow cytometry: 1×10^6 293F cells (negative control,left) and 293F (Transfection,right) cells were surface-stained with ABflo® 647 Rabbit anti-Human CD369/Dectin-1 mAb(A24272,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 293F(Transfection) cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human CD369/Dectin-1 mAb(A24272,5 μl/Test,right). |
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