ABflo® 647 Rabbit anti-Human CD48 mAb (100 T)

Background

This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Images

	Flow cytometry:1×10^6 K-562 cells (negative control,left) and Human PBMC (right) were surface-stained with ABflo® 647 Rabbit anti-Human CD48 mAb(A21946,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry:1×10^6 K-562 cells (negative control,left) and Daudi cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human CD48 mAb(A21946,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).

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