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ABflo® 647 Rabbit anti-Human FcεR1α mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | Fc epsilon receptor Ia |
| Gene Symbol: | FCER1A |
| Synonyms: | FCE1A; FcERI; FCERIA |
| Gene ID: | 2205 |
| UniProt ID: | P12319 |
| Clone ID: | 6Z4C8 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-205 of human FcεR1α (NP_001992.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-FCER1A Antibody |
Background
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
Images
 | Flow cytometry: 1×10^6 Jurkat cells (negative control,left) and HEL cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human FcεR1α mAb (A25411,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 HEL cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human FcεR1α mAb (A25411,5 μl/Test,right). |
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