ABflo® 647 Rabbit anti-Human Galectin 3 mAb (100 T)

Background

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Images

	Flow cytometry:1×10^6 Jurkat cells(Low Expression control,Left) and MCF7 cells (Right) were intracellularly-stained with ABflo® 647 Rabbit anti-Human Galectin 3 mAb(A23017,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells was used as blank control (red line).
	Flow cytometry:1×10^6 MCF7 cells were intracellularly-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human Galectin 3 mAb(A23017,5 μl/Test,right).
	Flow cytometry:1×10^6 Human PBMC were intracellularly-stained with ABflo® 647 Rabbit anti-Human Galectin 3 mAb(A23017,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry:1×10^6 Human PBMC were intracellularly-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human Galectin 3 mAb(A23017,5 μl/Test,right).

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