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ABflo® 647 Rabbit anti-Human Integrin-β1/CD29 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | Integrin subunit beta 1 |
| Gene Symbol: | ITGB1 |
| Synonyms: | CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA |
| Gene ID: | 3688 |
| UniProt ID: | P05556 |
| Clone ID: | 5V5P5 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-728 of human Integrin-β1/CD29 (NP_002202.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ITGB1 Antibody |
Background
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Images
 | Flow cytometry:1×10^6 RPMI 8226 cells (negative control,left) and A549 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human Integrin-β1/CD29 mAb(A22192,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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