Your shopping cart is empty!
ABflo® 647 Rabbit anti-Human Tie-2/CD202b mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | TEK receptor tyrosine kinase |
| Gene Symbol: | TEK |
| Synonyms: | TIE2; VMCM; GLC3E; TIE-2; VMCM1; CD202B |
| Gene ID: | 7010 |
| UniProt ID: | Q02763 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-745 of human Tie-2/CD202b (NP_000450.3). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TEK Antibody |
Background
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Images
 | Flow cytometry: 1×10^6 293T cells (negative control,left) and NTERA-2 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human Tie-2/CD202b mAb (A27390,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 NTERA-2 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human Tie-2/CD202b mAb (A27390,5 μl/Test,right). |
You may also be interested in:
Related Products
-10%
-16%
