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ABflo® 647 Rabbit anti-Mouse CD144/VE-Cadherin mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | cadherin 5 |
| Gene Symbol: | Cdh5 |
| Synonyms: | 7B4; Vec; VECD; Cd144; VEcad; VE-Cad |
| Gene ID: | 12562 |
| UniProt ID: | P55284 |
| Clone ID: | 1G9Q9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 46-592 of mouse CD144/VE-Cadherin (NP_033998.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cdh5 antibody |
Background
This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein die in utero due to vascular insufficiency, caused by increased endothelial apoptosis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8.
Images
 | Flow cytometry: 1×10^6 C2C12 cells (negative control,left) and bEnd.3 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Mouse CD144/VE-Cadherin mAb (A24893,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 bEnd.3 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse CD144/VE-Cadherin mAb (A24893,5 μl/Test,right). |
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