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Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 700. Ex:690nm. Em:713nm. |
Gene Name: | nerve growth factor receptor |
Gene Symbol: | NGFR |
Synonyms: | CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR |
Gene ID: | 4804 |
UniProt ID: | P08138 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-250 of human CD271/NGFR (NP_002498.1). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.02 mg/ml |
Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-NGFR Antibody |
Background
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Images
![]() | Flow cytometry: 1×10^6 K-562 cells (negative control,left) and SK-N-MC cells (right) were surface-stained with ABflo® 700 Rabbit anti-Human NGFR/CD271 mAb (A26369,5 μl/Test,orange line) or ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 SK-N-MC cells were surface-stained with ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,left) or ABflo® 700 Rabbit anti-Human NGFR/CD271 mAb (A26369,5 μl/Test,right). |
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