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ABflo® 700 Rabbit anti-Human CD55 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 700. Ex:690nm. Em:713nm. |
| Gene Name: | CD55 molecule (Cromer blood group) |
| Gene Symbol: | CD55 |
| Synonyms: | CR; TC; DAF; CROM; CHAPLE |
| Gene ID: | 1604 |
| UniProt ID: | P08174 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-353 of human CD55 (NP_000565.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD55 Antibody |
Background
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Images
 | Flow cytometry: 1×10^6 SH-SY5Y cells (negative control,left) and K-562 cells (right) were surface-stained with ABflo® 700 Rabbit anti-Human CD55 mAb (A26234,5 μl/Test,orange line) or ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 K-562 cells were surface-stained with ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,left) or ABflo® 700 Rabbit anti-Human CD55 mAb (A26234,5 μl/Test,right). |
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