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ABflo® 700 Rabbit anti-Human CD80/B7-1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 700. Ex:690nm. Em:713nm. |
| Gene Name: | CD80 molecule |
| Gene Symbol: | CD80 |
| Synonyms: | B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1 |
| Gene ID: | 941 |
| UniProt ID: | P33681 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-242 of human CD80/B7-1 (NP_005182.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD80 Antibody |
Background
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Images
 | Flow cytometry: 1×10^6 293F cells (negative control,left) and Raji cells (right) were surface-stained with ABflo® 700 Rabbit anti-Human CD80/B7-1 mAb (A26574,5 μl/Test,orange line) or ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 Raji cells were surface-stained with ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,left) or ABflo® 700 Rabbit anti-Human CD80/B7-1 mAb (A26574,5 μl/Test,right). |
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