| Reactivity: | M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial  | 
Synonyms:  | ACAD6, ACADVL, LCACD, VLCAD  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse ACADVL/VLCAD  | 
Uniprot ID:  | P50544  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW. / Observed MW.  | 71 kDa / 65 kDa  | 
Product Usage Information
WB  | Mouse, Rat  | 1: 500-1: 1000  | kidney, liver  | 
Background
Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains.
Images
  | Western blot analysis of ACADVL/VLCAD (GB114309) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |