Reactivity: | Human, Mouse |
Applications: | WB, IHC, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | acid phosphatase 1 |
Gene Symbol: | ACP1 |
Synonyms: | HAAP; LMWPTP; LMW-PTP; ACP1 |
Gene ID: | 52 |
UniProt ID: | P24666 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human ACP1 (NP_009030.1). |
Dilution: | WB 1:500-1:2000; IHC 1:50-1:100 |
Purification Method: | Affinity purification |
Concentration: | 0.25 mg/ml |
Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Documents: | Manual-ACP1 antibody |
Background
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Images
![]() | Western blot analysis of lysates from mouse liver, using ACP1 Rabbit pAb (A12390) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
![]() | Immunohistochemistry analysis of paraffin-embedded Mouse kidney using ACP1 Rabbit pAb (A12390) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
![]() | Immunohistochemistry analysis of paraffin-embedded Human liver damage using ACP1 Rabbit pAb (A12390) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
![]() | Immunohistochemistry analysis of paraffin-embedded Human stomach using ACP1 Rabbit pAb (A12390) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
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