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| Reactivity: | Human, Mouse |
| Applications: | WB, IF/IC, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Polyclonal antibody |
| Gene Name: | actin related protein 3 |
| Gene Symbol: | ACTR3 |
| Synonyms: | ARP3; Arp3 |
| Gene ID: | 10096 |
| UniProt ID: | P61158 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human Arp3 (NP_005712.1). |
| Dilution: | WB 1:500-1:2000; IF/IC 1:10-1:100 |
| Purification Method: | Affinity purification |
| Concentration: | 1.00 mg/ml |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ACTR3 antibody |
Background
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene.
Images
 | Western blot analysis of various lysates using Arp3 Rabbit pAb (A1064) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). |
 | Immunofluorescence analysis of HeLa cells using Arp3 Rabbit pAb (A1064). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining. |
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