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Anti-ADCY2 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Adenylate cyclase type 2 |
Synonyms: | ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, Kiaa1060, AC2, HBAC2, KIAA1060, MGC133314 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ADCY2 |
Uniprot ID: | Q80TL1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. / Observed MW. | 123 kDa / 124 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | brain, cerebellum |
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | hippocampus, kidney, brain |
Background
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors.
Images
| Western blot analysis of ADCY2 (GB114825) at dilution of 1: 300 |
| Immunohistochemistry of paraffin embedded mouse Hippocampus using ADCY2 (GB114825) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded rat kidney using ADCY2 (GB114825) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded rat kidney using ADCY2 (GB114825) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded mouse Brain using ADCY2 (GB114825) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |